Choline

  • Forms DNA and cell structures
  • Supports the central nervous system
  • Maintains 6 Step Liver Cleanse – Dr. Axe liver heath
  • Protects the brain
  • Improves physical performance and muscle-building
  • Promotes cardiovascular health
  • Promotes prenatal health
  • Ensures proper child development

Best Choline

Sale#1 Real Supplements Rated Best in 2020
NOW Supplements, Choline & Inositol 500 mg, Healthy Nerve Transmission*, Nervous System Health*, 100 Capsules
  • SUPPORTS HEALTHY NERVE TRANSMISSION*: Choline is necessary for normal synaptic transmission, brain health, and fatty acid metabolism in the liver.*
  • ASSISTS IN FATTY ACID METABOLISM*: Inositol is also essential for brain and nervous system health.*
  • CERTIFICATIONS/CLASSIFICATIONS: Kosher, Non-GMO, Soy Free
  • GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation).
  • Packaged in the USA by a family owned and operated company since 1968.
#2 Real Supplements Rated Best in 2020
Choline Bitartrate 650 mg 200 Veggie Capsules ( Vegan, Non-GMO & Gluten-Free) Supports Healthy Cognitive Functions & Mental Focus*
  • Choline Bitartrate Powder With 650 mg per Serving (serving is 2 caps) Max Supply (200 Veggie Capsules & 100 Day Supply .Providing 267 mg of Elemental Choline per serving. Suitable for Vegan/Vegetarian diets, Non-GMO, Gluten-free and all natural formulation.
  • Supports Cognitive Function* Supports Cellular Function* Supports Healthy Metabolism*.
  • Manufactured in the USA in a cGMP registered facility with the highest standards.
  • As a small family business, we fully understand the uncertainty and risk of trying new supplements. And this is why we go extra mile to source only the highest quality ingredients. Also, trust and transparency is at the forefront of our brand. We list every single ingredient on our products so that you can make an informative decision. Let us know if you have any questions or if can be of any service!
  • We source ingredients exclusively from partners who share our rigor for quality, choosing ingredients that meet stringent requirements, such as: identity, purity, potency and bioavailability, so you can achieve the maximum benefits.
#3 Real Supplements Rated Best in 2020
Standard Process Choline - Liver Support, Gallbladder Support, and Nervous System Supplement with Choline Bitartrate and Honey - 90 Tablets
  • Provides support for methylation reactions
  • Supports healthy liver and gallbladder function
  • Supports a healthy nervous system
  • Standard Process: High-quality products that work the way nature intended
Sale#4 Real Supplements Rated Best in 2020
Horbaach Choline Inositol 1000 mg (200 Capsules) | Non-GMO, Gluten Free Supplement
  • Non-GMO; Free of Gluten, Wheat, Yeast, Milk, Lactose and Soy
  • Choline & Inositol 1000 mg 200 Capsules; Great bulk size
  • Supports nervous system and cognitive health*
  • Supports healthy liver function and fat metabolism*
  • Superior cellular health formula*
Sale#5 Real Supplements Rated Best in 2020
Solgar Choline 350 mg, 100 Vegetable Capsules - Supports Healthy Brain & Cellular Function - Vegan, Gluten Free, Dairy Free, Kosher - 100 Servings
  • Healthy Brain Function; Choline, a member of the B Complex, is involved in the chemistry of the brain, where it is used to synthesize acetylcholine, a critical neurotransmitter required for brain function
  • Cellular Function; Choline is a component of cell membranes and provides key support for optimal cellular function
  • Metabolism & Liver Health; Choline also promotes normal fat metabolism and provides liver support; This formulation provides 350 mg of choline (as choline bitartrate) per serving
  • Gluten, Wheat & Dairy Free; Solgar Choline is vegan, kosher, and free of: gluten, wheat, dairy, soy, yeast, sugar, sodium, artificial flavor, sweetener, preservatives, and color; Suitable for vegetarians
  • The Gold Standard: For over 70 years, Solgar has been committed to quality, health, and well-being. Our mission is to create the finest nutritional supplements in small batches, through tireless research, using only the finest raw materials
#6 Real Supplements Rated Best in 2020
CDP Choline (Citicoline) Supplement, Pharmaceutical Grade, Made in USA (60 Capsules 300mg)
  • Promote Choline Levels; CDP Choline is an effective and potent Choline source
  • Support Memory; Retain more of what you learn, and recall memories with greater ease
  • Promote Cognitive Function; promotes working memory, focus, and mental energy
  • Made in the USA; Our CDP Choline is manufactured right here in the USA
Sale#7 Real Supplements Rated Best in 2020
Jarrow formulas Citicoline CDP Choline
  • Citicoline [stabilized CDP Choline (cytidine 5'diphosphocholine)] is a naturally occurring intermediate involved in the synthesis of phosphatidylcholine, a major constituent of the grey matter of brain tissue (30%)
  • Jarrow Formulas
Sale#8 Real Supplements Rated Best in 2020
Nature’s Way Choline & Inositol, Brain Health*, Cellular Energy*, 1,000 mg per Serving, 100 Capsules
  • BRAIN HEALTH & CELLULAR ENERGY.* With 1,000 mg choline and inositol per serving.
  • RESPONSIBLE PACKAGING. Bottle made with 97% post-consumer recycled materials. Please recycle.
  • GLUTEN-FREE. No sugar, salt, yeast-derived ingredients, wheat, dairy, or artificial colors, flavors, or preservatives.
#9 Real Supplements Rated Best in 2020
Thorne Research - Phosphatidyl Choline - Phospholipid Complex for Cell Membrane Support - 60 Gelcaps
  • Liver: Excellent source of choline for liver support*
  • Liver Protective: Protects liver cells from toxin-induced damage*
  • Cholesterol: Helps maintain already healthy levels of cholesterol*
  • Bile Flow: Promotes the healthy flow of bile*
  • Free From: Every Thorne product is made with the purest possible ingredients - without gluten or other major allergens (eggs, tree nuts, peanuts). This product also contains no soy, dairy, yeast, shellfish, or fish.
#10 Real Supplements Rated Best in 2020
Pure Synergy Choline Complex (60 Tablets) Choline Vitamin Made with Organic Veggies & Sprouts
  • Made with organic vegetables and sprouts, and fermented so it’s absorbed just like food
  • Promotes healthy cognitive function & supports brain & nervous system health
  • Supports healthy liver function as well as healthy bile & fat metabolism
  • Important for healthy prenatal brain development
  • Made with Organic Ingredients, Non-GMO, Gluten-Free, Vegan, Dairy-Free
#11 Real Supplements Rated Best in 2020
Choline & Inositol 1000mg - 200 Veggie Caps (100% Vegetarian, Non-GMO & Gluten-Free) . Supports Healthy Brain Functions*
  • Extra Strength Choline & Inositol 1000mg Per Serving (500 mg per veggie capsule)  Max Supply (200 Capsules & Over 100 Days Supply)  Vegetarian/vegan, Non-GMO, Gluten-free and all natural formulation
  • Supports Healthy Nerve Transmission* Supports Fatty Acid Metabolism* Supports Healthy Brain Function* Supports Healthy Cell Membranes* 
  • We source ingredients exclusively from partners who share our rigor for quality, choosing ingredients that meet stringent requirements, such as: identity, purity, potency and bioavailability, so you can achieve the maximum benefits.
  • Manufactured in the USA: manufactured in a cGMP registered facility with the highest standards. Only natural items are used in the creation of this product. We are a trusted brand - recognized for our excellent customer service
  • As a small family business, we fully understand the uncertainty and risk of trying new supplements. And this is why we go extra mile to source only the highest quality ingredients. Also, trust and transparency is at the forefront of our brand. We list every single ingredient on our products so that you can make an informative decision. Let us know if you have any questions or if can be of any service!
#12 Real Supplements Rated Best in 2020
Premium Choline - 500 mg - 120 Veggie Capsules - by Doctor Recommended Supplements - Supports Cognitive Health, Memory & More
  • Brain Function – Choline is necessary for proper mental function and can help delay memory loss and absentmindedness. Our supplement is formulated with only the highest-quality Choline to improve focus and alertness.*
  • Delay Fatigue – Help your body meet the demands of intense training. Athletes favor Choline to keep fatigue from slowing them down in the middle of training or performance and to assist muscle building and recovery for bodybuilders.*
  • Dietary Standards – Doctor Recommended Choline Supplements are a vegan-friendly and gluten-free way to support cellular health and mental sharpness.
  • Support Metabolism – Choline is naturally occurring in foods like liver and shrimp, and the body makes some, but most of us don’t get enough in our diets. Our Choline provides the amount needed to keep your body’s systems running well.*
  • Made in the USA – We want you to feel great about the safety and quality of your health and wellness supplements. We manufacture all of our health products in the USA lab so that you can feel confident taking them every day.
#13 Real Supplements Rated Best in 2020
Best Naturals Choline Bitartrate 650 mg (Non-GMO) for Healthy Cognitive Brain Function 180 Tablets
  • 100% MONEY BACK GUARANTEE – Try the Best - Risk Free! These Choline Supplement and covered by a no-questions asked money back guarantee.
  • Best Naturals Choline made with Non-GMO Choline which Supports mental acuity & energy, Supports healthy metabolism, Promotes cellular function, Supports nerve & liver health*
  • THE MOST BIO-AVAILABLE FORM OF CHOLINE - Best Naturals Choline contains a highly bioavailable form of choline that is easily absorb into body and give real effect.*
  • No Artificial Color, Flavor or Sweetener, No Preservatives, No Sugar, No Starch, No Corn, No Soy, No Egg, No Lactose, No Gluten, No Wheat, No Yeast, No Fish, No Sodium.
  • All Best Naturals products are manufactured in accordance with Good Manufacturing Practices (GMP), among the highest standards in the world -- Proudly Made in USA -- Purity & Potency Guaranteed
#14 Real Supplements Rated Best in 2020
Bulksupplements Choline L-Bitartrate Powder (500 Grams)
  • Boosts athletic endurance and Assists in muscle recovery*
  • Antioxidant and Promotes heart health*
  • Helps support the liver and Aids in maintaining healthy weight*
  • Supports memory & brain function*
  • Contributes to overall health & wellness*
#15 Real Supplements Rated Best in 2020
Nutricost CDP Choline (Citicoline) 300mg, 120 Veggie Capsules - Non-GMO, Vegan Friendly, Gluten Free
  • 300mg Of CDP Choline In Every (Veggie) Capsule
  • Easy To Swallow
  • 120 Servings of CDP Choline in Every Bottle
  • Manufactured In a GMP Compliant, FDA Registered Facility
  • Gluten Free & Non-GMO
#16 Real Supplements Rated Best in 2020
NOW Supplements, Alpha GPC 300 mg with Bioavailable Source of Choline, 60 Veg Capsules
  • BIOAVAILABLE SOURCE OF CHOLINE: 600 mg of Alpha GPC per serving
  • SUPPORTS MENTAL ACUITY*: Promotes normal cognitive function*
  • CERTIFICATIONS/CLASSIFICATIONS: Dairy Free, Egg Free, Made without Gluten, Nut Free, Vegan
  • GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation)
  • Packaged in the USA by a family owned and operated company since 1968
#17 Real Supplements Rated Best in 2020
Nutricost Pure Choline Bitartrate Powder 500 Grams
  • Pure, High Quality Choline Bitartrate Powder
  • Manufactured in a GMP Compliant, FDA Registered Facility
  • 500 Grams of Choline Bitartrate Per Bottle
  • Serving Size: 1 Scoop (Included)
  • Gluten Free & Non-GMO
#18 Real Supplements Rated Best in 2020
Phosphatidylcholine 1,200mg – 210 Softgels – Enhanced Version of Sunflower and Soy Lecithin - Non-GMO, Made and Tested in the USA to Support Brain Health by Double Wood Supplements
  • Made in the USA and Tested for Purity; Our Phosphatidyl Choline (PC) soft gels are manufactured right here in New York and testing is available upon request
  • Supports Cognitive Function; Studies have shown that PhosphatidylCholine may help enhance memory and overall cognitive function by increasing levels of choline and acetylcholine in the brain
  • Supports the Aging Brain; Low levels of Phosphadtylcholine (PCC) have been linked to decreased cognitive function and impaired mental abilities, especially as one ages
  • Promotes Liver Health; Low levels of Phosphatidylcholine are linked to poor liver function and increased PC may promote liver regeneration
Sale#19 Real Supplements Rated Best in 2020
Alpha GPC 600mg + Uridine, a Choline Enhancer. Better Than Alpha-GPC or Uridine Аlone. Best Alpha GPC Choline: 2in1, Soy Free, No Fillers, USA. Best Choline Form, 60 Pills, Money Back Guarantee
  • THE MOST BIOAVAILABLE CHOLINE SUPPLEMENT. Alpha GPC (choline alfoscerate) is the most bioavailable form of choline (40.3% choline), better than Phosphatidylcholine, CDP choline, Choline Bitartrate. Uridine Monophosphate increases the absorption of Alpha - GPC, making it more potent. The two work synergistically to boost memory and overall cognitive function, being a better choice than each on its own, any other form of choline or choline inositol*
  • SOY FREE ALPHA GPC, BETTER CHOICE EVEN FOR PEOPLE WITHOUT SOY ALLERGIES. Our Alpha GPC is from sunflower lecithin, not soy lecithin as in leading competitors. This is important because lecithin from sunflowers is derived by use of cold press, while lecithin from soy is derived via harsh chemicals with adverse side effects*
  • THE ONLY CHOICE WITHOUT INACTIVE INGREDIENTS OTHER THAN A VEGETABLE CAPSULE. At Dr. Maxwell we are concerned with maximum wellness so we avoid the nasty ingredients of competitors: silicon dioxide, stearic acid, magnesium stearate, starch, etc.*
  • BRAIN HEALTH, MEMORY, NERVOUS SYSTEM, HEART, LIVER, METABOLISM & MUSCLE SUPPORT. Dr. Maxwell’s Alpha GPC Choline + Uridine Mr Happy stack is an excellent source of choline, an essential nutrient needed for optimal health. Choline plays a key role in many processes and is required to make acetylcholine, a neurotransmitter involved in memory, muscle movement and recovery, regulating heartbeat and other basic functions*
  • SATISFACTION GUARANTEED OR YOUR MONEY BACK. Made in the USA from the highest quality, non-GMO, pure, vegan ingredients in a cGMP and FDA-registered facility. Free from soy, gluten, milk, eggs, wheat, peanuts, sweeteners, shellfish and sugar. No fillers
Sale#20 Real Supplements Rated Best in 2020
Citicoline CDP Choline 1000mg | 60 Capsules | Highest Potency Per Capsule | Non-GMO, Gluten Free Supplement | by Carlyle
  • Non-GMO; Free of Gluten, Wheat, Milk, Lactose and Soy
  • Each capsule in our 60 Capsule bottle of Citicoline CDP Choline Supplement contains 500 mg
  • This extra strength CDP Choline supplement delivers 1000 mg per serving
  • Pills from CDP-Choline bulk powder (citicoline sodium); citicoline is a known B-Vitamin
  • Citicoline is a naturally-occuring chemical that supports healthy cognitive brain function*

Best 8 Benefits of Choline

Choline is a water-soluble micronutrient that has many benefits. It promotes the structural integrity of cells and enables them to send out signals throughout the body. Choline also supports several processes, including metabolism, DNA replication, brain development, muscle movement, and liver function, as well as increases energy. Choline also aids in the production of numerous hormones and chemicals such as acetylcholine (a neurotransmitter) and found in body fat.

Choline can be found naturally in many foods, including eggs, beef, salmon, liver, and cauliflower. Your body also produces choline, and it is thought that increased intake of folate leads to greater choline production. A deficiency in choline can cause problems with the nervous, endocrine, digestive, and reproductive systems.

Let’s take a closer look at some of the benefits of choline.

1. Forms DNA and cell structures

Choline aids the body in fat absorption, which is then used to create cell structures such as the cell membrane. Without choline, cells cannot hold their structure and transmit signals to other cells. This micronutrient is also needed to create DNA. Paired with folate, choline helps produce methyl groups, which the body them uses to form genetic material.

2. Supports the central nervous system

The central nervous system is comprised of the brain and the spinal cord. Choline aids in the formation of neurotransmitters like acetylcholine, which is used to help various nerves and muscles function. One specific function choline plays a part in is signaling; it allows nerves to transmit signals across the body quickly and accurately, and it also helps protect neuronal membranes from damage. Acetylcholine in particular plays a role in memory and learning, so a choline deficiency can lead to poor memory, lack of concentration, mood swings, and other cognitive impairments, particularly in old age.

3. Maintains 6 Step Liver Cleanse – Dr. Axe liver heath

Choline is needed to transport fats such as cholesterol and triglycerides from the liver throughout the body and helps prevent the buildup of unhealthy fat in the liver. It is also responsible for producing LDL cholesterol. Though too much LDL cholesterol is bad for your health, some is still needed; without it, the liver will store excess fat. Low levels of choline have also been associated with higher risk of liver damage and even failure.

4. Protects the brain

Another benefit of choline is its restorative power for the brain. Because of its role in building cell membranes and neurotransmitters, it helps preserve neurons, thus maintaining memory and preventing dementia and other forms of mental decline. Brain elasticity, like acetylcholine, naturally declines with age, but increased intake of choline helps the brain retain its elasticity and produce enough acetylcholine to maintain proper function. In fact, some studies have suggested that low acetylcholine levels may lead to cognitive impairments such as Alzheimer’s 11; some medications used to treat Alzheimer’s actually mimic the effect of choline on the nervous system.

5. Improves physical performance and muscle-building

Choline aids in focus and concentration, improves mental energy and ability, and quickens mental processing and reaction times. In addition to improving mental stamina, choline enhances physical aspects as well, such as physical energy, sleep cycles, and recovery time after strenuous activity. It has also been shown to prevent fatigue and relieve muscle aches.

6. Promotes cardiovascular health

Along with folate, choline helps convert the amino acid homocysteine; this prevents the body from accumulating too much fat and can reduce the risk of heart attack and stroke. When coupled with lecithin, choline also reduces the risk of heart disease. Research also suggests that this combination may also reduce triglycerides and LDL cholesterol, but further study is needed.

7. Promotes prenatal health

Choline is consumed rapidly by a developing fetus, which uses the nutrient in the development of the brain, nerve channels, and cell structures. Some studies even suggest that increased fetal consumption of choline can produce a sharper mind and reduce the risk of cognitive abnormalities, whereas a choline deficiency can lead to neural tube defects and other developmental problems. This nutrient is found naturally in breast milk and is frequently added to infant formulas so the infant’s nervous system can develop properly. Choline, folate, and other B vitamins all work together. If a fetus is deficient in the latter two nutrients, choline, a methyl donor, can help fill in until proper amounts of those minerals are obtained.

8. Ensures proper child development

Neuroplasticity, the brain’s ability to form and maintain new neural connections, is greatly benefited by choline. Developing children naturally have plastic brains, meaning their brains are extremely malleable when it comes to learning new skills, thinking logically, and concentration. Choline is essential for healthy neurotransmitters in children. When children receive sufficient amounts of choline, their concentration, mathematical skills, social skills, creative thinking, and retention are improved. Some research even suggests that choline can prevent learning and behavioral disabilities such as ADHD.


Real Supplements gives you the best Choline on the market today. Our top-rated lists are fresh and current so you get the best options.

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